Heterozygosity mapping for human dominant trait variants
نویسندگان
چکیده
منابع مشابه
PrediXcan: Trait Mapping Using Human Transcriptome Regulation
Genome-wide association studies (GWAS) have identified thousands of variants robustly associated with complex traits. However, the biological mechanisms underlying these associations are, in general, not well understood. We propose a gene-based association method called PrediXcan that directly tests the molecular mechanisms through which genetic variation affects phenotype. The approach estimat...
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ژورنال
عنوان ژورنال: Human Mutation
سال: 2019
ISSN: 1059-7794,1098-1004
DOI: 10.1002/humu.23765